TargetMol

Iberin

Product Code:
 
TAR-T15544
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15544-1mg1mg£118.00
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TAR-T15544-5mg5mg£180.00
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TAR-T15544-10mg10mg£230.00
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TAR-T15544-25mg25mg£334.00
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TAR-T15544-50mg50mg£465.00
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TAR-T15544-100mg100mg£646.00
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Quantity:
TAR-T15544-500mg500mg£1,259.00
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This product comes from: United States.
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Further Information

Bioactivity:
Iberin is a sulfoxide analogue of sulforaphane and is a naturally occurring member of the isothiocyanate family. It also inhibits cell survival (IC50: 2.3 μM in HL60 cell).
CAS:
505-44-2
Formula:
C5H9NOS2
Molecular Weight:
163.25
Pathway:
Metabolism
Purity:
0.98
SMILES:
CS(=O)CCCN=C=S
Target:
Endogenous Metabolite

References

1. Jakubikova J, et al. Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines. Anticancer Res. 2005 Sep-Oct;25(5):3375-86. 2. Jadhav U, et al. Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cells. 3. Jadhav U, et al. Dietary isothiocyanate iberin inhibits growth and induces apoptosis in human glioblastoma cells. J Pharmacol Sci. 2007 Feb;103(2):247-51. 4. Jakobsen TH, et al. Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorumsensing inhibitor of Pseudomonas aeruginosa. Appl Environ Microbiol. 2012 Apr;78(7):2410-21. 5. Munday R, et al. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. J Agric Food Chem. 2004 Apr 7;52(7):1867-71.