TargetMol

Nemiralisib

Product Code:
 
TAR-T15431
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Nemiralisib is a potent and highly selective inhibitor of PI3Kδ (pKi: 9.9).
CAS:
1254036-71-9
Formula:
C26H28N6O
Molecular Weight:
440.551
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
CC(C)N1CCN(Cc2cnc(o2)-c2cc(cc3[nH]ncc23)-c2cccc3[nH]ccc23)CC1
Target:
PI3K

References

1. Down K et al. Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase ? for the Treatment of Respiratory Disease. J Med Chem. 2015 Sep 24;58(18):7381-99.