TargetMol

Ritodrine hydrochloride

Product Code:
 
TAR-T1433
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1433-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T1433-100mg100mg£117.00
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TAR-T1433-200mg200mg£155.00
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Further Information

Bioactivity:
Ritodrine binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine is a phenethylamine derivative with tocolytic activity. Specifically, ritodrine probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contractions. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions.
CAS:
23239-51-2
Formula:
C17H21NO3?HCl
Molecular Weight:
323.82
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9989
SMILES:
Cl.C[C@H](NCCc1ccc(O)cc1)[C@H](O)c1ccc(O)cc1
Target:
Adrenergic Receptor

References

1. Tanaka N, et al. J Med Chem. 2001 Apr 26;44(9):1436-45.