TargetMol

Acitretin

Product Code:
 
TAR-T1330
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1330-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1330-100mg100mg£160.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Acitretin is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.
CAS:
55079-83-9
Formula:
C21H26O3
Molecular Weight:
326.436
Pathway:
Apoptosis; Autophagy; Metabolism
Purity:
0.9995
SMILES:
COc1cc(C)c(C=CC(C)=CC=CC(C)=CC(O)=O)c(C)c1C
Target:
Apoptosis; Retinoid Receptor; Autophagy

References

1. Tippmann F, et al. FASEB J, 2009, 23(6), 1643-1654. 2. Silva FS, et al. Toxicology, 2013, 306, 93-100. 3. Lin XY, et al. J Cell Mol Med, 2009, 13(9A), 2888-2898. 4. Cotler S, et al. Xenobiotica, 1992, 22(11), 1229-1237. 5. Eisenhardt EU, et al. Drug Metab Dispos, 1994, 22(1), 26-30. 6. Qiu Y, Sun Y, Xu D, et al. Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue[J]. EBioMedicine. 2018, 37: 344-355.