TargetMol

OICR-0547

Product Code:
 
TAR-T12290
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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Further Information

Bioactivity:
OICR-0547 is a closely related derivative of OICR-9429. OICR-9429 is a novel small-molecule Wdr5-MLL interaction antagonist.
CAS:
1801873-49-3
Formula:
C28H29F3N4O4
Molecular Weight:
542.559
Purity:
0.98
SMILES:
FC(F)(F)c1cc(=O)[nH]cc1C(=O)Nc1cc(ccc1N1CCOCC1)-c1cccc(CN2CCOCC2)c1

References

1. Grebien F, et al. Pharmacological targeting of the Wdr5-MLL interaction in C/EBP? N-terminal leukemia. Nat Chem Biol. 2015 Aug;11(8):571-578.