TargetMol

Cyproterone acetate

Product Code:
 
TAR-T1167
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1167-100mg100mg£97.00
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Quantity:
TAR-T1167-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1167-250mg250mg£114.00
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This product comes from: United States.
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Further Information

Bioactivity:
Cyproterone binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. Cyproterone Acetate is the acetate salt of a synthetic steroidal antiandrogen with weak progestational and antineoplastic activities. This agent also exerts progestational agonist properties at the level of the pituitary that reduce luteinizing hormone (LH), resulting in reductions in testicular androgen secretion and serum testosterone levels. Treatment with cyproterone alone results in incomplete suppression of serum testosterone levels.Cyproterone binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. Cyproterone Acetate is the acetate salt of a synthetic steroidal antiandrogen with weak progestational and antineoplastic activities. This agent also exerts progestational agonist properties at the level of the pituitary that reduce luteinizing hormone (LH), resulting in reductions in testicular androgen secretion and serum testosterone levels. Treatment with cyproterone alone results in incomplete suppression of serum testosterone levels.
CAS:
427-51-0
Formula:
C24H29ClO4
Molecular Weight:
416.94
Pathway:
Endocrinology/Hormones
Purity:
0.9843
SMILES:
[C@]12([C@@H]3[C@@H](C3)C(=O)C=C2C(=C[C@@H]2[C@@H]1CC[C@]1([C@H]2CC[C@]1(OC(=O)C)C(=O)C)C)Cl)C
Target:
Androgen Receptor

References

1. Sonneveld E, et al. Toxicol Sci. 2005, 83(1), 136-148. 2. Attardi BJ, et al. Mol Cell Endocrinol. 2010, 328(1-2), 16-21. 3. Arafa NM. Pak J Biol Sci. 2010, 13(20), 966-976. 4. Santiago-Moreno J, et al. J Endocrinol. 2012. 5. Aleem M, et al. Contraception. 2005, 71(5), 379-391.