TargetMol

GNF-6231

Product Code:
 
TAR-T11444
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11444-5mg5mg£113.00
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TAR-T11444-10mg10mg£125.00
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TAR-T11444-25mg25mg£164.00
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TAR-T11444-50mg50mg£229.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blocks Wnt signaling.
CAS:
1243245-18-2
Formula:
C24H25FN6O2
Molecular Weight:
448.502
Pathway:
Stem Cells
Purity:
0.98
SMILES:
CC(=O)N1CCN(CC1)c1ccc(NC(=O)Cc2cnc(c(C)c2)-c2ccnc(F)c2)nc1
Target:
Porcupine

References

Cheng D et al. Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors. ACS Med Chem Lett. 2016 May 10;7(7):676-80.