TargetMol

3,4-Dihydroxybenzylamine hydrobromide

Product Code:
 
TAR-T10104
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10104-100mg100mg£103.00
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Quantity:
TAR-T10104-1mL1 mL * 10 mM (in DMSO)£111.00
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Further Information

Bioactivity:
3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase activity in melanoma cells and displays growth inhibitory activity in melanoma cell lines with varying degrees of tyrosinase activity.
CAS:
16290-26-9
Formula:
C7H10BrNO2
Molecular Weight:
220.066
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint;
Purity:
0.9728
SMILES:
Br.NCc1ccc(O)c(O)c1
Target:
DNA/RNA Synthesis

References

1. Prezioso JA1,et al.Effects of tyrosinase activity on the cytotoxicity of 3,4-dihydroxybenzylamine and buthionine sulfoximine in human melanoma cells.Pigment Cell Res. 1990 Mar-Apr;3(2):49-54. 2. Mlchael M. Wick,et al. 3,4-Dihydroxybenzylamine: Antitumor Activity Against A Dopamine Analog B16 Melanoma. 3. FitzGerald GB, et al. 3,4-Dihydroxybenzylamine: an improved dopamine analog cytotoxic for melanoma cells in part through oxidation products inhibitory to dna polymerase.J Invest Dermatol. 1983 Feb;80(2):119-23.