TargetMol

Dicoumarol

Product Code:
 
TAR-T0809
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0809-500mg500mg£103.00
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Further Information

Bioactivity:
Dicumarol is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxidereductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.
CAS:
66-76-2
Formula:
C19H12O6
Molecular Weight:
336.299
Pathway:
Metabolism; PI3K/Akt/mTOR signaling
Purity:
0.999
SMILES:
Oc1c(Cc2c(O)c3ccccc3oc2=O)c(=O)oc2ccccc12
Target:
Dehydrogenase; NADPH; PDK

References

1. Jaiswal AK. Arch Biochem Biophys. 2000, 375(1):62-8.