TargetMol

Procaine hydrochloride

Product Code:
 
TAR-T0802
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T0802-500mg500mg£104.00
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TAR-T0802-1g1g£111.00
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Further Information

Bioactivity:
Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.
CAS:
51-05-8
Formula:
C13H20N2O2?HCl
Molecular Weight:
272.77
Pathway:
Cell Cycle/Checkpoint; Neuroscience; Membrane transporter/Ion channel; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein
Purity:
0.99
SMILES:
Cl.CCN(CC)CCOC(=O)c1ccc(N)cc1
Target:
Histone Demethylase; 5-HT Receptor; DNA/RNA Synthesis; Sodium Channel; NMDAR; AChR

References

1. Br?u ME ME, et al. Anesth Analg, 1998, 87(4), 885-889. 2. Hahnenkamp K, et al. Br J Anaesth, 2006, 96(1), 77-87. 3. Wang H, et al. Eur J Pharmacol, 2010, 630(1-3), 29-33. 4. Fan P, et al. Neuropharmacology, 1994, 33(12), 1573-1579. 5. Zahradn?kov? A, et al. Biophys J. 1993 Apr;64(4):1991-12003.