TargetMol

Ac-DEVD-CHO

Product Code:
 
TAR-TQ0146
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0146-1mg1mg£125.00
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TAR-TQ0146-5mg5mg£261.00
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TAR-TQ0146-10mg10mg£351.00
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TAR-TQ0146-25mg25mg£546.00
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TAR-TQ0146-50mg50mg£749.00
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This product comes from: United States.
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Further Information

Bioactivity:
Ac-DEVD-CHO is a selective Caspase-3 inhibitor (Ki: 230 pM).
CAS:
169332-60-9
Formula:
C20H30N4O11
Molecular Weight:
502.477
Pathway:
Apoptosis; Proteases/Proteasome
Purity:
0.98
SMILES:
[H][C@@](CC(O)=O)(NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@]([H])(CC(O)=O)NC(C)=O)C(C)C)C=O
Target:
Caspase

References

Jinglin Wang, et al. A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice. Oncotarget. 2017 Jan 3; 8(1): 610-623. Long-gang He, et al. Sinomenine induces apoptosis in RAW 264.7 cell-derived osteoclasts in vitro via caspase-3 activation. Acta Pharmacol Sin. 2014 Feb; 35(2): 203-210. Liu LX, et al. The effect of caspase-3 inhibitor on the concentrations of serum inflammatory cytokines in sepsis related acute kidney injury induced by peritoneal cavity infection in mice. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2010 Dec;22(12):736-9. Garcia-Calvo M, et al.nhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273(49):32608-13.