TargetMol

CU-CPD107

Product Code:
 
TAR-T35349
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35349-1mg1mg£122.00
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TAR-T35349-5mg5mg£181.00
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TAR-T35349-10mg10mg£245.00
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TAR-T35349-25mg25mg£390.00
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TAR-T35349-50mg50mg£524.00
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TAR-T35349-100mg100mg£707.00
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Further Information

Bioactivity:
CU-CPD107 is a selective agonist of toll-like receptor 8 (TLR8) and also shows activation activity against ssRNA ligands. CU-CPD107 acts as an inhibitor of TLR8 signaling in the presence of R848 (IC50=13.7 uM). CU-CPD107 exhibited coagonist activity in the presence of ssRNA, while CU-CPD107 alone could not affect TLR8 signal transduction.
CAS:
2573912-32-8
Formula:
C16H21IN2O2
Molecular Weight:
400.26
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
0
Target:
TLR

References

Yang Y, et al. Tetrasubstituted imidazoles as incognito Toll-like receptor 8?a(nta)gonists. Nat Commun. 2021 Jul 16;12(1):4351.