TargetMol

Betulin

Product Code:
 
TAR-T3121
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3121-50mg50mg£111.00
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Quantity:
TAR-T3121-100mg100mg£128.00
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This product comes from: United States.
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Further Information

Bioactivity:
Betulin (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is found in birch sap as well.
CAS:
473-98-3
Formula:
C30H50O2
Molecular Weight:
442.728
Pathway:
Apoptosis; Metabolism
Purity:
0.999
SMILES:
CC(=C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)[C@@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@H]12
Target:
Apoptosis; Endogenous Metabolite; Lipid; Fatty Acid Synthase

References

1. Kr?l, S., Kie?bus, M., Rivero-M?ller, A., & Stepulak, A. (2015). Comprehensive Review on Betulin as a Potent Anticancer Agent.?Biomed Research International,?2015, 1-11. doi: 10.1155/2015/584189 2. Drag M, et al. Comparision of the Cytotoxic Effects of Birch Bark Extract, Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines. Molecules. 2009 Apr 24;14(4):1639-51. 3. Ma C, et al. Protective effect of betulin on cognitive decline in streptozotocin (STZ)-induced diabetic rats. Neurotoxicology. 2016 Dec;57:104-111. 4. Guo, Chuansheng, et al. Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages [J]. Immunity. 2018 Nov 20;49(5):842-856.e7.