TargetMol

Honokiol DCA

Product Code:
 
TAR-T27551
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27551-50mg50mg£704.00
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Quantity:
TAR-T27551-100mg100mg£962.00
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This product comes from: United States.
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Further Information

Bioactivity:
Honokiol DCA is an inhibitor of DRP1 phosphorylation. Honokiol DCA stimulates a phenotype suggestive of respiration through mitochondrial normalization and demonstrating activity in Vemurafenib-resistant melanoma in vivo.
CAS:
1620160-42-0
Formula:
C22H18Cl4O4
Molecular Weight:
488.18
Purity:
0.98
SMILES:
ClC(Cl)C(=O)Oc1c(CC=C)cc(-c2ccccc2)c(OC(=O)C(Cl)Cl)c1CC=C

References

1. Bonner MY, Karlsson I, Rodolfo M, Arnold RS, Vergani E, Arbiser JL. Honokiol bis-dichloroacetate (Honokiol DCA) demonstrates activity in vemurafenib-resistant melanoma in vivo. Oncotarget. 2016 Mar 15;7(11):12857-68. doi: 10.18632/oncotarget.7289. PubMed PMID: 26871475; PubMed Central PMCID: PMC4914326.