TargetMol

Litorin

Product Code:
 
TAR-T20604
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T20604-50mg50mg£736.00
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Further Information

Bioactivity:
Litorin, an amphibian bombesin peptide derivative, is found to suppress the nutriment, to stimulate the contraction of smooth muscle, to stimulate gastrin, gastric acid, and pancreatic secretion.
CAS:
55749-97-8
Formula:
C51H68N14O11S
Molecular Weight:
1085.25
Purity:
0.98
SMILES:
CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCC(=O)N1)C(C)C)C(N)=O

References

1. Yurt Lambrecht F, Durkan K, Ozg?r A, G?nd?z C, Avc? CB, Susluer SY. In vitro evaluation of (99m)Tc-EDDA/tricine-HYNIC-Q-Litorin in gastrin-releasing peptide receptor positive tumor cell lines. J Drug Target. 2013 May;21(4):383-8. doi: 10.3109/1061186X.2012.757772. Epub 2013 Jan 10. PubMed PMID: 23301856. 2. Falconieri Erspamer G, Severini C. Litorin-like peptides in the skin of five phyllomedusa species other than Phyll.sauvagei and Phyll.rohdei. Pharmacol Res Commun. 1987 May;19(5):319-25. PubMed PMID: 3628456. 3. Barra D, Falconieri Erspamer G, Simmaco M, Bossa F, Melchiorri P, Erspamer V. Rohdei-litorin: a new peptide from the skin of Phyllomedusa rohdei. FEBS Lett. 1985 Mar 11;182(1):53-6. PubMed PMID: 3838283. 4. Durkan K, Lambrecht FY, Unak P. Radiolabeling of bombesin-like peptide with 99mTc: 99mTc-litorin and biodistribution in rats. Bioconjug Chem. 2007 Sep-Oct;18(5):1516-20. Epub 2007 Aug 31. PubMed PMID: 17760415.