TargetMol

JAK2 JH2 Tracer

Product Code:
 
TAR-T19017
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19017-50mg50mg£1,669.00
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Further Information

Bioactivity:
JAK2 JH2 Tracer is a fluorescent probe for the JAK2 JH2 domain (Kd: 0.2 μM).
CAS:
2101955-00-2
Formula:
C38H27F2N7O6S
Molecular Weight:
747.73
Purity:
0.98
SMILES:
CN(Cc1ccc(Nc2nc(N)n(n2)C(=O)c2c(F)cccc2F)cc1)C(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12

References

1. Newton AS, et al. JAK2 JH2 Fluorescence Polarization Assay and Crystal Structures for Complexes with Three Small Molecules. ACS Med Chem Lett. 2017 May 17;8(6):614-617.