TargetMol

Genistein

Product Code:
 
TAR-T1737
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1737-50mg50mg£101.00
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TAR-T1737-100mg100mg£114.00
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TAR-T1737-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T1737-500mg500mg£148.00
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This product comes from: United States.
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Further Information

Bioactivity:
Genistein is an isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA TOPOISOMERASES, TYPE II), with antineoplastic and antitumor activities.
CAS:
446-72-0
Formula:
C15H10O5
Molecular Weight:
270.24
Pathway:
Apoptosis; Metabolism; Tyrosine Kinase/Adaptors; Autophagy; JAK/STAT signaling; Angiogenesis
Purity:
0.9969
SMILES:
Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O
Target:
Apoptosis; EGFR; Endogenous Metabolite; Autophagy

References

1. Akiyama T, et al. J Biol Chem, 1987, 262(12), 5592-5595. 2. Linassier C, et al. Biochem Pharmacol, 1990, 39(1), 187-193. 3. Dang ZC, et al. J Biol Chem, 2003, 278(2), 962-967. 4. Lamartiniere CA, et al. J Nutr, 2002, 132(3), 552S-558S. 5. Wang Y, et al. Radiat Res, 2006, 166(1 Pt 1), 73-80. 6. Jalili C, et al. Effect of Genistein on reproductive parameter and serum nitric oxide levels in morphine-treated mice. Int J Reprod Biomed (Yazd). 2016 Feb;14(2):95-102. 7. Ding S, et al. Environmentally Relevant Dose of Bisphenol A Does Not Affect Lipid Metabolism and Has No Synergetic or Antagonistic Effects on Genistein's Beneficial Roles on Lipid Metabolism. PLoS One. 2016 May 12;11(5):e0155352. 8. Zhou H, Ning Y, Zeng G, et al. Curcumin promotes cell cycle arrest and apoptosis of acute myeloid leukemia cells by inactivating AKT[J]. Oncology Reports. 2021, 45(4): 1-1.