TargetMol

PK14105

Product Code:
 
TAR-T16547
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T16547-5mg5mg£246.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T16547-50mg50mg£830.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T16547-100mg100mg£1,267.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
PK14105 is a biological evaluation as a potential radioligand for PET studies of PBBS receptors. PK 14105 was injected into rats with unilaterally lesioned striata, show that PK 14105 rapidly crosses the blood-brain-barrier and that there is marked retention of radioactivity in the lesioned striatum not seen in the unlesioned striatum or cerebellar vermis. It can also inhibit receptor ligands, calcium channel ligands, and co-transporter in all salivary glands.
CAS:
107257-28-3
Formula:
C21H20FN3O3
Molecular Weight:
381.407
Purity:
0.98
SMILES:
CCC(C)N(C)C(=O)c1cc2ccccc2c(n1)-c1cc(ccc1F)[N+]([O-])=O

References

1. Pascali C et al. The radiosynthesis of [18F]PK 14105 as an alternative radioligand for peripheral type benzodiazepine binding sites. Int J Rad Appl Instrum A. 1990;41(5):477-82. 2. Franklin C. Wong et al. Affinity Labeling of Membrane Receptors Using Tissue-Penetrating Radiations. Biomed Res Int. 2013, 503095.