TargetMol

Oxamflatin

Product Code:
 
TAR-T16415
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16415-50mg50mg£791.00
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TAR-T16415-100mg100mg£1,171.00
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This product comes from: United States.
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Further Information

Bioactivity:
Oxamflatin is an effective inhibitor of HDAC (IC50: 15.7 nM).
CAS:
151720-43-3
Formula:
C17H14N2O4S
Molecular Weight:
342.37
Pathway:
Chromatin/Epigenetic; DNA Damage/DNA Repair
Purity:
0.98
SMILES:
ONC(=O)C=CC#Cc1cccc(NS(=O)(=O)c2ccccc2)c1
Target:
HDAC

References

1. Kim YB, et al. Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase. Oncogene. 1999 Apr 15;18(15):2461-70. 2. Wang YL, et al. HDAC Inhibitor Oxamflatin Induces Morphological Changes and has Strong Cytostatic Effects in Ovarian Cancer Cell Lines. Curr Mol Med. 2016;16(3):232-42. 3. Faghihloo E, et al. The effect of oxamflatin on the E-cadherin expression in gastric cancer cell line. Cancer Gene Ther. 2016 Nov;23(11):396-399.