TargetMol

NSC16168

Product Code:
 
TAR-T16351
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16351-5mg5mg£370.00
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TAR-T16351-50mg50mg£1,564.00
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Quantity:
TAR-T16351-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer. NSC16168 is a specific ERCC1-XPF inhibitor (IC50: 0.42 μM).
CAS:
6837-93-0
Formula:
C17H15NO9S3
Molecular Weight:
473.49
Pathway:
Endocrinology/Hormones
Purity:
0.98
SMILES:
Cc1ccc(cc1)S(=O)(=O)Oc1cc(cc2cc(cc(N)c12)S(O)(=O)=O)S(O)(=O)=O
Target:
Estrogen/progestogen Receptor

References

1. Arora S, et al. Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells. Oncotarget. 2016 Nov 15;7(46):75104-75117.