TargetMol

GSK2194069

Product Code:
 
TAR-T15429
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15429-50mg50mg£537.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T15429-1mL1 mL * 10 mM (in DMSO)£551.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
GSK2194069 is a specific inhibitor of the β-ketoacyl reductase (KR) activity of hFAS (IC50: 7.7 ? 4.1 nM in an assay detecting released CoA).
CAS:
1332331-08-4
Formula:
C25H24N4O3
Molecular Weight:
428.492
Pathway:
Others|Metabolism
Purity:
0.98
SMILES:
O=C(C1CC1)N1CC[C@@H](Cc2n[nH]c(=O)n2-c2ccc(cc2)-c2ccc3occc3c2)C1
Target:
Others|Fatty Acid Synthase|NADPH

References

1. Hardwicke MA, et al. A human fatty acid synthase inhibitor binds ?-ketoacyl reductase in the keto-substrate site. Nat Chem Biol. 2014 Sep;10(9):774-9.