TargetMol

EZ-482

Product Code:
 
TAR-T15265
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15265-50mg50mg£704.00
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Quantity:
TAR-T15265-100mg100mg£1,131.00
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Further Information

Bioactivity:
EZ-482 is a novel ligand of apolipoprotein (apoE). EZ-482 binds to apoE4 by a unique N-terminal allosteric effect and it also binds to sites on apoE in the C-terminal domain (Kds: 5-10 μM for apoE3 and apoE4).
CAS:
1016456-76-0
Formula:
C23H19ClN4O5S
Molecular Weight:
498.94
Purity:
0.98
SMILES:
Cn1nc(CC(=O)Nc2cc(ccc2O)S(=O)(=O)Nc2cccc(Cl)c2)c2ccccc2c1=O

References

1. Tridib Mondal, et al. ApoE: In Vitro Studies of a Small Molecule Effector. Biochemistry. 2016 May 10;55(18):2613-21.