TargetMol

BI605906

Product Code:
 
TAR-T14567
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14567-50mg50mg£774.00
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Quantity:
TAR-T14567-100mg100mg£1,131.00
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This product comes from: United States.
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Further Information

Bioactivity:
BI605906 is an inhibitor of IKKβ. When assayed at 0.1 mM ATP, the IC50 value is 380 nM.
CAS:
960293-88-3
Formula:
C17H22F2N4O3S2
Molecular Weight:
432.5
Pathway:
NF-κb
Purity:
0.98
SMILES:
CCC(F)(F)c1cc(nc2sc(C(N)=O)c(N)c12)N1CCC(CC1)S(C)(=O)=O
Target:
IκB/IKK

References

1. Clark K, et al. Novel cross-talk within the IKK family controls innate immunity. Biochem J. 2011 Feb 15;434(1):93-104. 2. Cameron AR, et al. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status. Circ Res. 2016 Aug 19;119(5):652-65.