TargetMol

S130

Product Code:
 
TAR-T12819
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12819-5mg5mg£304.00
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TAR-T12819-50mg50mg£1,163.00
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Quantity:
TAR-T12819-100mg100mg£1,564.00
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This product comes from: United States.
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Further Information

Bioactivity:
S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.
CAS:
1160852-22-1
Formula:
C24H25N3O2
Molecular Weight:
387.483
Pathway:
Proteases/Proteasome
Purity:
0.98
SMILES:
CCN(CC)CCCNC(=O)c1cnc2C(=O)c3ccccc3-c3cccc1c23
Target:
Cysteine Protease

References

1. Fu Y, et al. Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo. Autophagy. 2018 Sep 20:1-17.