TargetMol

Necrostatin 2 S enantiomer

Product Code:
 
TAR-T12203
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12203-50mg50mg£790.00
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Further Information

Bioactivity:
Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2
CAS:
852391-20-9
Formula:
C13H12ClN3O2
Molecular Weight:
277.71
Purity:
0.98
SMILES:
CN1C(=O)N[C@@H](Cc2c[nH]c3c(Cl)cccc23)C1=O

References

1. Teng X, Keys H, Jeevanandam A, Structure-activity relationship study of [1,2,3]thiadiazole necroptosis inhibitors. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6836-40. 2. Takahashi N, et al. Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models. Cell Death Dis. 2012 Nov 29;3:e437. 3. Jagtap PG, Degterev A, Choi S, Structure-activity relationship study of tricyclic necroptosis inhibitors. J Med Chem. 2007 Apr 19;50(8):1886-95. 4. Teng X, Degterev A, Jagtap P, Structure-activity relationship study of novel necroptosis inhibitors. Bioorg Med Chem Lett. 2005 Nov 15;15(22):5039-44.