TargetMol

Ethionamide

Product Code:
 
TAR-T1165
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1165-200mg200mg£95.00
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TAR-T1165-500mg500mg£111.00
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TAR-T1165-1mL1 mL * 10 mM (in DMSO)£113.00
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TAR-T1165-1g1g£136.00
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This product comes from: United States.
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Further Information

Bioactivity:
Ethionamide is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthesis of mycolic acid, a saturated fatty acid found in the bacterial cell wall, thereby inhibiting bacterial cell wall synthesis. This eventually leads to bacterial cell wall disruption and cell lysis. Ethionamide may be bacteriostatic or bactericidal in action, depending on the concentration of the drug at the site of infection and the susceptibility of the organism involved.
CAS:
536-33-4
Formula:
C8H10N2S
Molecular Weight:
166.24
Pathway:
Microbiology/Virology; Metabolism; oxidation-reduction
Purity:
0.9992
SMILES:
CCc1cc(ccn1)C(N)=S
Target:
Dehydrogenase; CAT; Antibacterial; Antibiotic

References

1. Vale N, et al. Curr Drug Metab, 2013, 14(1), 151-158. 2. Cordeiro Rde A, et al. Can J Microbiol,2015, 61(11), 827-836. 3. Vale N, et al. Eur J Pharm Biopharm,2012, 81(2), 314-323. 4. Vannelli TA, et al. J Biol Chem,2002, 277(15), 12824-12829.