TargetMol

GC7 Sulfate

Product Code:
 
TAR-T11372
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11372-5mg5mg£108.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T11372-10mg10mg£142.00
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Quantity:
TAR-T11372-25mg25mg£229.00
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Quantity:
TAR-T11372-50mg50mg£309.00
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Quantity:
TAR-T11372-100mg100mg£454.00
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Quantity:
TAR-T11372-500mg500mg£914.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
CAS:
150417-90-6
Formula:
C8H22N4O4S
Molecular Weight:
270.35
Pathway:
Autophagy
Purity:
0.98
SMILES:
OS(O)(=O)=O.NCCCCCCCNC(N)=N
Target:
Autophagy

References

1. Bandino A, et al. Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients. Cell Oncol (Dordr). 2014 Dec;37(6):387-98. 2. Lou B, et al. N1-guanyl-1,7-diaminoheptane (GC7) enhances the therapeutic efficacy of doxorubicin by inhibiting activation of eukaryotic translation initiation factor 5A2 (eIF5A2) and preventing the epithelial-mesenchymal transition in hepatocellular carcinoma cells. Exp Cell Res. 2013 Oct 15;319(17):2708-17.