TargetMol

Eicosatetraynoic acid

Product Code:
 
TAR-T11169
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T11169-50mg50mg£647.00
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TAR-T11169-100mg100mg£870.00
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Further Information

Bioactivity:
Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM. Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively).
CAS:
1191-85-1
Formula:
C20H24O2
Molecular Weight:
296.41
Pathway:
Neuroscience; Immunology/Inflammation
Purity:
0.98
SMILES:
CCCCCC#CCC#CCC#CCC#CCCCC(O)=O
Target:
COX

References

1. Hammarstr?m S, et al. Selective inhibition of platelet n-8 lipoxygenase by 5,8,11-eicosatriynoic acid. Biochim Biophys Acta. 1977 Jun 22;487(3):517-9. 2. Kliewer SA, et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell. 1995 Dec 1;83(5):813-9.