TargetMol

C75

Product Code:
 
TAR-T10657
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10657-25mg25mgEnquire
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TAR-T10657-50mg50mgEnquire
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TAR-T10657-1mg1mg£138.00
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TAR-T10657-1mL1 mL * 10 mM (in DMSO)£155.00
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TAR-T10657-5mg5mg£229.00
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TAR-T10657-10mg10mg£309.00
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This product comes from: United States.
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Further Information

Bioactivity:
C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).
CAS:
218137-86-1
Formula:
C14H22O4
Molecular Weight:
254.32
Pathway:
Metabolism
Purity:
0.9884
SMILES:
O=C1OC(CCCCCCCC)C(C(=O)O)C1=C
Target:
Fatty Acid Synthase

References

1. Rae C, et al. Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy. Radiat Res. 2015 Nov;184(5):482-93. 2. Makowski K, et al. Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity. Chirality. 2013 May;25(5):281-7. 3. Gao S, et al. Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5628-33. 4. Thupari JN, et al. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9498-502.