TargetMol

Domperidone

Product Code:
 
TAR-T0082
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0082-50mg50mg£101.00
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Quantity:
TAR-T0082-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T0082-100mg100mg£114.00
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TAR-T0082-200mg200mg£144.00
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Quantity:
TAR-T0082-500mg500mg£189.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which - among others - regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and rhomboid fossa).
CAS:
57808-66-9
Formula:
C22H24ClN5O2
Molecular Weight:
425.92
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9973
SMILES:
Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1
Target:
Dopamine Receptor

References

1. Miles ED, et al. J Agric Food Chem,2011, 59(17), 9691-9699. 2. Sudakov SK, et al. Bull Exp Biol Med,2013, 155(6), 705-707. 3. Castro JR, et al. Am J Vet Res,2010, 71(3), 281-287. 4. Jones KL, et al. J Anim Sci,2003, 81(10), 2568-2574. 5. Redmond LM, et al. Am J Vet Res,1994, 55(5), 722-729.