TargetMol

Thalidomide 4-fluoride

Product Code:
 
TAR-T7755
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7755-500mg500mg£94.00
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Further Information

Bioactivity:
Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
CAS:
835616-60-9
Formula:
C13H9FN2O4
Molecular Weight:
276.223
Pathway:
Immunology/Inflammation; NF-κb
Purity:
0.98
SMILES:
Fc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Target:
IRAK

References

Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.