TargetMol

Bexarotene

Product Code:
 
TAR-T6410
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6410-25mg25mg£108.00
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TAR-T6410-50mg50mg£120.00
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TAR-T6410-100mg100mg£144.00
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TAR-T6410-200mg200mg£169.00
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Quantity:
TAR-T6410-500mg500mg£280.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Bexarotene is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).
CAS:
153559-49-0
Formula:
C24H28O2
Molecular Weight:
348.486
Pathway:
Autophagy; Metabolism
Purity:
0.99
SMILES:
Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
Target:
Retinoid Receptor; Autophagy

References

Nieto-Rementer?a N, et al. Br J Dermatol. 2009 Mar;160(3):519-26. Zeng X, Zhu S, Lu W, et al. Target identification among known drugs by deep learning from heterogeneous networks. Chemical Science. 2020, 11(7): 1775-1797. Li Y, et al. Br J Cancer, 2008, 98(8), 1380-1388. Zhang C, et al. Clin Cancer Res, 2002, 8(5), 1234-1240. Ren Q, Xie X, Zhao C, et al. 2, 2?, 4, 4?-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPAR? Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation. Chemical Research in Toxicology. 2022 Qiu Y, Sun Y, Xu D, et al. Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue[J]. EBioMedicine. 2018, 37: 344-355. Zeng X, Zhu S, Lu W, et al. Target identification among known drugs by deep learning from heterogeneous networks[J]. Chemical Science. 2020, 11(7): 1775-1797. Qiu Y, Sun Y, Xu D, et al. Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue. EBioMedicine. 2018, 37: 344-355.