TargetMol

2,6-Diaminoheptanedioic acid

Product Code:
 
TAR-T4889
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4889-100mg100mg£99.00
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Further Information

Bioactivity:
Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into peptidoglycan of gram negative bacteria and is the attachment point for Braun's lipoprotein (BLP or Murein Lipoprotein). BLP is found in gram-negative cell walls and is one of the most abundant membrane proteins. BLP is bound at its C-terminal end (a lysine) by a covalent bond to the peptidoglycan layer (specifically to diaminopimelic acid molecules) and is embedded in the outer membrane by its hydrophobic head (a cysteine with lipids attached). BLP tightly links the two layers and provides structural integrity to the bacterial outer membrane. Diaminopimelic acid can be found in human urine or feces due to the lysis or enzymatic breakdown of gram negative gut microbes.
CAS:
583-93-7
Formula:
C7H14N2O4
Molecular Weight:
190.199
Pathway:
; Metabolism
Purity:
0.9995
SMILES:
NC(CCCC(N)C(O)=O)C(O)=O
Target:
Endogenous Metabolite

References

Borruat G , Roten C A H , Fay L B , et al. A High-Performance Liquid Chromatography Method for the Detection of Diaminopimelic Acid in Urine[J]. Analytical Biochemistry, 2001, 291(1):11-16. Lida S . Gordonia otitidis sp. nov. isolated from a patent with externarl otitis[J]. Int. J. Syst. Evol. Microbiol. 2005, 55. Hamaker B R , Rivera K , Morales E , et al. Effect of Dietary Fiber and Starch on Fecal Composition in Preschool Children Consuming Maize, Amaranth, or Cassava Flours[J]. J Pediatr Gastroenterol Nutr, 1991, 13(1):59-66.