TargetMol

PD-1/PD-L1-IN-NP19

Product Code:
 
TAR-T36900
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36900-5mg5mg£324.00
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TAR-T36900-50mg50mg£1,267.00
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Quantity:
TAR-T36900-100mg100mg£1,966.00
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Further Information

Bioactivity:
PD-1/PD-L1-IN-NP19 is a PD-1/PD-L1 inhibitor, with an IC50 of 12.5 nM for human PD-1/PD-L1 interaction. PD-1/PD-L1-IN-NP19 could activate the immune microenvironment in tumor, which may contribute to its antitumor effects[1].
CAS:
2377916-66-8
Formula:
C33H31ClN2O4
Molecular Weight:
555.06
Pathway:
Apoptosis|Cell Cycle/Checkpoint|Immunology/Inflammation
Purity:
0.98
SMILES:
N/A
Target:
PD-1/PD-L1

References

Cheng B, et, al. Discovery of Novel Resorcinol Dibenzyl Ethers Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction As Potential Anticancer Agents. J Med Chem. 2020 Jul 15.