TargetMol

uPSEM 817 tartrate

Product Code:
 
TAR-T36811
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36811-5mg5mg£1,171.00
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TAR-T36811-50mg50mg£2,303.00
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Quantity:
TAR-T36811-100mg100mg£3,042.00
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This product comes from: United States.
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Further Information

Bioactivity:
Selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channel agonist (EC50 values are 0.3 and 0.5 nM, respectively). Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).
CAS:
2341833-14-3
Formula:
C16H19N3O.C4H6O6
Molecular Weight:
419.43
Purity:
0.98
SMILES:
CCCOC1=NC2=C(N=C1)C=C(C3=C2)C4CNCC3C4.O[C@@H](C(O)=O)[C@@H](O)C(O)=O

References

Magnus et al (2019) Ultrapotent chemogenetics for research and potential clinical applications. Science 364 PMID:30872534