TargetMol

FD-211

Product Code:
 
TAR-T36693
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36693-25mg25mg£1,234.00
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Further Information

Bioactivity:
FD-211 is a δ lactone originally isolated from M. lutea with anticancer activity.1 It is cytotoxic to adriamycin-susceptible P388, T-24, HeLa, A549, and HL-60 cancer cells (IC50s = 4, 0.5, 1, 1, and 0.2 μg/ml, respectively), as well as adriamycin-resistant HL-60/ADR cells (IC50 = 0.1 μg/ml). FD-211 also inhibits DNA, RNA, and protein synthesis in HeLa cells (IC50 = 1.25 μg/ml for all).
CAS:
162341-24-4
Formula:
C13H16O4
Molecular Weight:
236.3
Purity:
0.98
SMILES:
O[C@H]1[C@@H](/C=C/C)O[C@]2([H])C(C(O[C@H]2/C=C/C)=O)=C1

References

Nozawa, O., Okazaki, T., Sakai, N., et al. A novel bioactive ? lactone FD-211. Taxonomy, isolation and characterization. J. Antibiot. (Tokyo) 48(2), 113-118 (1995).