TargetMol

SDZ 224-015

Product Code:
 
TAR-T36534
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36534-5mg5mg£337.00
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TAR-T36534-50mg50mg£1,532.00
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Quantity:
TAR-T36534-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1. SDZ 224-015 possesses anti-COVID-19 activity, targeting Mpro (IC50 of 30 nM)[1][2].
CAS:
161511-45-1
Formula:
C30H35Cl2N3O9
Molecular Weight:
652.52
Purity:
0.98
SMILES:
N/A

References

P R Elford, et al. Reduction of inflammation and pyrexia in the rat by oral administration of SDZ 224-015, an inhibitor of the interleukin-1 beta converting enzyme. Br J Pharmacol. 1995 Jun;115(4):601-6. Martin A Redhead, et al. Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19. Sci Rep. 2021 Jun 24;11(1):13208.