TargetMol

Zenarestat

Product Code:
 
TAR-T35299
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35299-5mg5mg£244.00
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TAR-T35299-50mg50mg£986.00
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TAR-T35299-100mg100mg£1,532.00
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This product comes from: United States.
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Further Information

Bioactivity:
Zenarestat (CI-1014, FK-366, FR-74366) is an aldose reductase inhibitor being studied as a treatment for diabetic neuropathy and cataracts.
CAS:
112733-06-9
Formula:
C17H11BrClFN2O4
Molecular Weight:
441.64
Purity:
0.98
SMILES:
OC(=O)Cn1c2cc(Cl)ccc2c(=O)n(Cc2ccc(Br)cc2F)c1=O

References

Zenarestat. FK 366, FR 74366, FR 901366. Drugs R D. 2002;3(4):235-7. Review. PubMed PMID: 12455199. Tanaka Y, Shimojyo H, Hata T, Hashimoto M, Noguchi H. Toxicokinetics of zenarestat, an aldose reductase inhibitor in animals and man. Xenobiotica. 1994 May;24(5):461-71. PubMed PMID: 8079505. Kihara M, Mitsui Y, Shioyama M, Hasegawa T, Takahashi M, Takakura S, Minoura K, Kawamura I. Effect of zenarestat, an aldose reductase inhibitor, on endoneurial blood flow in experimental diabetic neuropathy of rat. Neurosci Lett. 2001 Sep 14;310(2-3):81-4. PubMed PMID: 11585572. Shimoshige Y, Ikuma K, Yamamoto T, Takakura S, Kawamura I, Seki J, Mutoh S, Goto T. The effects of zenarestat, an aldose reductase inhibitor, on peripheral neuropathy in Zucker diabetic fatty rats. Metabolism. 2000 Nov;49(11):1395-9. PubMed PMID: 11092500.