TargetMol

18 α-Glycyrrhetinic acid

Product Code:
 
TAR-T2745
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2745-25mg25mg£104.00
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Quantity:
TAR-T2745-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T2745-50mg50mg£124.00
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Further Information

Bioactivity:
Enoxolone (INN, BAN; also known as glycyrrhetinic acid) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb licorice. It is used in flavoring and it masks the bitter taste of drugs like aloe and quinine. It is effective in the treatment of peptic ulcer and also has expectorant (antitussive) properties.
CAS:
1449-05-4
Formula:
C30H46O4
Molecular Weight:
470.694
Pathway:
Apoptosis; NF-κb; Proteases/Proteasome; Ubiquitination
Purity:
0.9983
SMILES:
CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O
Target:
Apoptosis; NF-κB; Proteasome

References

1. Parida PK, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3865-8. 2. Huang S, Cao B, Zhang J, et al. Induction of ferroptosis in human nasopharyngeal cancer cells by cucurbitacin B: molecular mechanism and therapeutic potential[J]. Cell Death & Disease . 2021, 12(3): 1-13.