TargetMol

SAFit1

Product Code:
 
TAR-T16835
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16835-5mg5mg£371.00
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Quantity:
TAR-T16835-50mg50mg£1,532.00
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Quantity:
TAR-T16835-100mg100mg£2,287.00
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This product comes from: United States.
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Further Information

Bioactivity:
SAFit1 is an inhibitor of FK506 binding protein 51 (FKBP51)-specific (Ki: 4?0.3 nM).
CAS:
1643125-32-9
Formula:
C42H53NO11
Molecular Weight:
747.882
Purity:
0.98
SMILES:
COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](C2CCCCC2)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC

References

1. Gaali S, et al. Selective inhibitors of the FK506-binding protein 51 by induced fit. Nat Chem Biol. 2015 Jan;11(1):33-7. 2. Sidibeh CO, et al. FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes. Endocrine. 2018 Oct;62(1):116-128.