TargetMol

Thiostrepton

Product Code:
 
TAR-T1679
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1679-25mg25mg£95.00
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TAR-T1679-50mg50mg£104.00
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TAR-T1679-1mL1 mL * 10 mM (in DMSO)£108.00
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TAR-T1679-100mg100mg£117.00
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This product comes from: United States.
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Further Information

Bioactivity:
Thiostrepton is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in dermatologic disorders.
CAS:
1393-48-2
Formula:
C72H85N19O18S5
Molecular Weight:
1664.89
Pathway:
Microbiology/Virology; DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.9933
SMILES:
CCC(C)C1NC2C=Cc3c(cc(nc3C2O)C(=O)OC(C)C2NC(=O)c3csc(n3)C(NC(=O)C3CSC(=N3)C(NC(=O)C(NC(=O)c3csc(n3)C3(CCC(=NC3c3csc2n3)c2nc(cs2)C(=O)NC(=C)C(=O)NC(=C)C(N)=O)NC(=O)C(C)NC(=O)C(=C)NC(=O)C(C)NC1=O)C(C)O)=CC)C(C)(O)C(C)O)C(C)O
Target:
DNA/RNA Synthesis; Antibacterial; Antibiotic

References

1. Kuiper EG, Conn GL. J Biol Chem. 2014 Sep 19;289(38):26189-200. 2. Lai W, Zhu W, Li X, et al. GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway[J]. Laboratory Investigation . 2020: 1-10. 3. Zhou Z, Chen H, Xie R, et al. Epigenetically modulated FOXM 1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer[J]. Molecular oncology. 2019 Apr;13(4):873-893.