TargetMol

RF9

Product Code:
 
TAR-T16738
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T16738-100mg100mgEnquire
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Further Information

Bioactivity:
RF9 is an effective and selective antagonist of the Neuropeptide FF receptor (Kis: 58?5 and 75?9 nM for hNPFF1R and hNPFF2R, respectively).
CAS:
876310-60-0
Formula:
C26H38N6O3
Molecular Weight:
482.629
Purity:
0.98
SMILES:
NC(=N)NCCC[C@H](NC(=O)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

References

1. Simonin F, et al. RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):466-71. 2. Wang YQ, et al. Neuropeptide FF receptors antagonist, RF9, attenuates opioid-evoked hypothermia in mice. Peptides. 2008 Jul;29(7):1183-90.