TargetMol

M443

Product Code:
 
TAR-T15943
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15943-5mg5mg£370.00
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Quantity:
TAR-T15943-50mg50mg£1,468.00
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Quantity:
TAR-T15943-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
M443 is an irreversible and specific MRK inhibitor (IC50<125 nM).
CAS:
1820684-31-8
Formula:
C31H30F3N7O2
Molecular Weight:
589.623
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.98
SMILES:
Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)C3CCCN(C3)C(=O)C=C)c2)cc(c1)C(F)(F)F
Target:
Adrenergic Receptor

References

1. Markowitz D, et al. Pharmacological Inhibition of the Protein Kinase MRK/ZAK Radiosensitizes Medulloblastoma. Mol Cancer Ther. 2016 Aug;15(8):1799-808.