TargetMol

L-AP4

Product Code:
 
TAR-T15692
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15692-25mg25mg£993.00
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Further Information

Bioactivity:
L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).
CAS:
23052-81-5
Formula:
C4H10NO5P
Molecular Weight:
183.1
Pathway:
Neuroscience
Purity:
0.98
SMILES:
N[C@@H](CCP(O)(O)=O)C(O)=O
Target:
GluR

References

1. Selvam C, et al. Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites. J Med Chem. 2018 Mar 8;61(5):1969-1989. 2. Chen SR, et al. Distinct roles of group III metabotropic glutamate receptors in control of nociception and dorsal horn neurons in normal and nerve-injured Rats. J Pharmacol Exp Ther. 2005 Jan;312(1):120-6.