TargetMol

AICAR

Product Code:
 
TAR-T1477
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1477-25mg25mg£95.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1477-50mg50mg£104.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1477-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1477-100mg100mg£123.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1477-200mg200mg£149.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1477-500mg500mg£254.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Acadesine is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes.
CAS:
2627-69-2
Formula:
C9H14N4O5
Molecular Weight:
258.234
Pathway:
Chromatin/Epigenetic; Autophagy; PI3K/Akt/mTOR signaling; Stem Cells
Purity:
0.9971
SMILES:
NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N
Target:
Mitophagy; YAP; AMPK; Autophagy

References

1. Corton JM, et al. Eur J Biochem, 1995, 229(2), 558-565. 2. Camp?s C, et al. Blood, 2003, 101(9), 3674-368 3. Robert G, et al. PLoS One, 2009, 4(11), e7889. 4. Fabian TC, et al. Surgery, 1996, 119(3), 302-315. 5. Mathew JP, et al. J Thorac Cardiovasc Surg, 1995, 109(3), 448-456. 6. Fan C, Feng J, Tang C, et al. Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage[J]. 2020, 11(1): 1-22. 7. Shang Z, Zhang T, Jiang M, et al. High-carbohydrate, High-fat Diet-induced Hyperlipidemia Hampers the Differentiation Balance of Bone Marrow Mesenchymal Stem Cells by Suppressing Autophagy via the AMPK/mTOR Pathway in Rat Models[J]. 2020.