TargetMol

AZD2906

Product Code:
 
TAR-T14374
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14374-5mg5mg£370.00
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TAR-T14374-50mg50mg£1,532.00
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TAR-T14374-100mg100mg£2,079.00
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Further Information

Bioactivity:
AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively[1]. AZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats.
CAS:
1034148-15-6
Formula:
C26H25FN4O3
Molecular Weight:
460.509
Purity:
0.98
SMILES:
COc1ccc(cn1)[C@@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)[C@H](C)NC(=O)C1CC1

References

1. Hayes JE, et al. Micronucleus induction in the bone marrow of rats by pharmacological mechanisms. I: glucocorticoid receptor agonism. Mutagenesis. 2013 Mar;28(2):227-32.