TargetMol

QX-314 chloride

Product Code:
 
TAR-T12608
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12608-25mg25mg£109.00
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Quantity:
TAR-T12608-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T12608-50mg50mg£136.00
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Quantity:
TAR-T12608-100mg100mg£177.00
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This product comes from: United States.
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Further Information

Bioactivity:
QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.
CAS:
5369-03-9
Formula:
C16H27ClN2O
Molecular Weight:
298.86
Pathway:
Membrane transporter/Ion channel
Purity:
0.9984
SMILES:
[Cl-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C
Target:
Sodium Channel

References

1. Rivera-Acevedo RE, et al. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro. Anesthesiology. 2011 Jun;114(6):1425-34. 2. Talbot MJ, et al. Intracellular QX-314 inhibits calcium currents in hippocampal CA1 pyramidal neurons. J Neurophysiol. 1996 Sep;76(3):2120-4.