TargetMol

MK-4074

Product Code:
 
TAR-T12062
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12062-100mg100mgEnquire
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TAR-T12062-50mg50mg£2,238.00
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This product comes from: United States.
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Further Information

Bioactivity:
MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM).
CAS:
1039758-22-9
Formula:
C33H31N3O6
Molecular Weight:
565.626
Purity:
0.98
SMILES:
COc1cc(cc2n(cc(C)c12)C1CC1)C(=O)N1CCC2(CC1)CC(=O)c1cc(ccc1O2)-c1cncc(c1)C(O)=O

References

1. Kim CW, et al. Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation. Cell Metab. 2017 Aug 1;26(2):394-406.e6.