TargetMol

CDK8-IN-1

Product Code:
 
TAR-T10740
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10740-1mg1mg£164.00
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TAR-T10740-5mg5mg£303.00
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TAR-T10740-1mL1 mL * 10 mM (in DMSO)£326.00
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TAR-T10740-10mg10mg£436.00
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TAR-T10740-25mg25mg£675.00
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TAR-T10740-50mg50mg£922.00
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Quantity:
TAR-T10740-100mg100mg£1,219.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).
CAS:
1629633-48-2
Formula:
C11H8F3N3O
Molecular Weight:
255.2
Pathway:
Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
NC(=O)c1[nH]cc(c1C(F)(F)F)-c1ccncc1
Target:
CDK

References

Han X, et al. Discovery of potent and selective CDK8 inhibitors through FBDD approach. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4488-4492.