TargetMol

Flumequine

Product Code:
 
TAR-T1060
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1060-50mg50mg£97.00
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TAR-T1060-100mg100mg£107.00
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TAR-T1060-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T1060-200mg200mg£121.00
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This product comes from: United States.
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Further Information

Bioactivity:
Flumequine is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, enzymes necessary to separate bacterial DNA, thereby inhibiting cell division.
CAS:
42835-25-6
Formula:
C14H12FNO3
Molecular Weight:
261.252
Pathway:
Microbiology/Virology; DNA Damage/DNA Repair
Purity:
0.994
SMILES:
CC1CCc2cc(F)cc3c2n1cc(C(O)=O)c3=O
Target:
Topoisomerase; Antibacterial; Antibiotic

References

1. Kashida Y, et al. Toxicol Sci, 2002, 69(2), 317-321. 2. Giraud E, et al. J Med Microbiol, 2004, 53(Pt 9), 895-901. 3. Martinsen B, et al. Antimicrob Agents Chemother, 1995, 39(5), 1059-1064. 4. Migliore L, et al. Chemosphere, 2000, 40(7), 741-750. 5. Hansen MK, et al. J Vet Pharmacol Ther, 2000, 23(3), 163-168. 6. Aller-Mor?n LM, et al. Evaluation of the in vitro activity of flumequine against field isolates of Brachyspira hyodysenteriae. Res Vet Sci. 2015 Dec;103:51-3.